What is the proper administration protocol for TXA?

The administration of Tranexamic Acid (TXA) is crucial in trauma settings to reduce the risk of bleeding. The correct protocol involves administering 1 gram of TXA diluted in 100ml of normal saline over a period of 10 minutes. This method of administration ensures that the drug is delivered at an appropriate rate, allowing for effective absorption into the bloodstream while minimizing potential side effects.

TXA works by inhibiting fibrinolysis, which is the breakdown of blood clots. Prompt and proper administration is critical in trauma patients, especially in cases of significant hemorrhage, as it helps stabilize the patient's condition by preventing further bleeding.

In contrast, other options do not adhere to the recognized administration guidelines for TXA, either by altering the dilution, concentration, or infusion rate, which could affect its efficacy and safety profile.